Academic Research Journal of
Agricultural Science and Research
Academic Research Journal of Agricultural Science and Research
Vol. 4(3), pp. 85-92. March, 2016.
Full Length Research
Hystopathological and clinical investigations of five gemmo-derivatives from plants and their biotherapeutical properties
Anca Daniela Raiciu1, Doina Camelia Vrabie2, Simona Negreş3, Mariana Popescu1, Crișan Iuliana1, Ştefan Manea1, Ştefan-Ovidiu Dima4 *
1S.C. Hofigal Export-Import S.A., 2 Intrarea Serelor,042124 Bucharest, Romania, firstname.lastname@example.org
2Sfântul Ioan Clinique and Emergency Hospital Bucharest, 13 Vitan Bȃrzești, 042122 Bucharest, Romania
3University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania
4INCDCP-ICECHIM, 202 Splaiul Independenţei, 060021 Bucharest, Romania *email@example.com
Corresponding author: Ştefan-Ovidiu Dima
Accepted 25 April 2016
Gemmo-therapy, a branch of biotherapy, is a treatment method which is specific by the fact that uses fresh embryonic plant tissue, also known as meristematic tissues. Gemmo-derivatives from branches of Rosmarinus officinalis (rosemary), branches of Vaccinium myrtillus (blueberry), ament of Salix Alba (white willow), shoots of Ribes nigrum (black currant) and buds of Betula Pubescens (downy birch) were obtained as glycerin macerates. Histologic studies were carried out in kidney and liver, and clinical tests were performed by orally administrating a dose of 1 g/kg body weight over 14 days. The interpretation of the variation of animals’ weight was performed by t-Student test. The results indicated no negative effects of the studied gemmo-derivatives and no significant changes in motor behavior, body weight, and appearance of treated mice.
Key words: gemmo-therapy, bio-pharmacy, histopathology, meristematic tissues, extracts
How to cite this article: Raiciu AD, Vrabie DC, Negreş S, MPopescu M, Iuliana C, Manea S, Dima S-O (2016). Hystopathological and clinical investigations of five gemmo-derivatives from plants and their biotherapeutical properties. Acad. Res. J. Agri. Sci. Res. 4(3): 85-92.