Academic Research Journal of Agricultural Science and Research
 

Academic Research Journal of Agricultural Science and Research 

Vol. 4(3), pp. 85-92. March, 2016.

ISSN: 2360-7874 

 DOI: 10.14662/ARJASR2016.007

Full Length Research

Hystopathological and clinical investigations of five gemmo-derivatives from plants and their biotherapeutical properties

Anca Daniela Raiciu¹, Doina Camelia Vrabie², Simona Negreş³, Mariana Popescu¹, Crișan Iuliana¹, Ştefan Manea¹, Ştefan-Ovidiu Dima⁴ *

¹S.C. Hofigal Export-Import S.A., 2 Intrarea Serelor,042124 Bucharest, Romania, daniela_raiciu@yahoo.com

²Sfântul Ioan Clinique and Emergency Hospital Bucharest, 13 Vitan Bȃrzești, 042122 Bucharest, Romania

³University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania

⁴INCDCP-ICECHIM, 202 Splaiul Independenţei, 060021 Bucharest, Romania *dr.ovidiu.dima@gmail.com

Corresponding author: Ştefan-Ovidiu Dima

E-mail: dr.ovidiu.dima@gmail.com

Accepted 25 April 2016

Gemmo-therapy, a branch of biotherapy, is a treatment method which is specific by the fact that uses fresh embryonic plant tissue, also known as meristematic tissues. Gemmo-derivatives from branches of Rosmarinus officinalis (rosemary), branches of Vaccinium myrtillus (blueberry), ament of Salix Alba (white willow), shoots of Ribes nigrum (black currant) and buds of Betula Pubescens (downy birch) were obtained as glycerin macerates. Histologic studies were carried out in kidney and liver, and clinical tests were performed by orally administrating a dose of 1 g/kg body weight over 14 days. The interpretation of the variation of animals’ weight was performed by t-Student test. The results indicated no negative effects of the studied gemmo-derivatives and no significant changes in motor behavior, body weight, and appearance of treated mice.

Key words: gemmo-therapy, bio-pharmacy, histopathology, meristematic tissues, extracts

How to cite this article: Raiciu AD, Vrabie DC, Negreş S, MPopescu M, Iuliana C, Manea S, Dima S-O (2016). Hystopathological and clinical investigations of five gemmo-derivatives from plants and their biotherapeutical properties. Acad. Res. J. Agri. Sci. Res. 4(3): 85-92.

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